At Manhattan Pain Medicine, pain is evaluated before it is treated. Our approach is diagnosis-first and discovery-led, designed to understand what is generating the pain, how it developed, and why it has not resolved. Care is organized through three connected phases: Discovery, Treatment, and Maintenance.
Learn how Dr. Siefferman approaches pain diagnosis and treatment through a personalized, step-by-step process focused on identifying the root cause, reducing pain, and helping patients achieve lasting relief.
Our team organizes conditions and treatments into related zones of expertise to make it easier to explore the care paths most relevant to your symptoms and goals.
Use the zone tags above to browse dedicated pages for each focus area, including services, providers, and what to expect during treatment.
Hi, I’m Dr. Jason Siefferman and I would like to speak to you about our approach to pain diagnosis and treatment at Manhattan Pain Medicine. At its core, pain is a signal. When it’s new, it’s pretty straightforward. We can identify the reason, treat that, get you better. When it’s been going on for some period of time, that’s when the complexity develops. At that point, patients aren’t just dealing with the original issue anymore. There’s often compensatory patterns that have developed, changes in the nervous system based on how that signal is being processed and then other layers that make the pain feel harder to understand and harder to treat.
Our approach is structured, thoughtful, and collaborative. We need to understand the impacts that it has on the rest of your life because that all filters right back into the experience of pain. Our process typically moves through three phases: discovery, treatment, and maintenance. The discovery phase is where we seek comprehensive, complex, thorough, complete diagnosis. Essentially, we want to understand what’s going on and why.
The next phase is treatment. During the treatment phase, there’s always a little bit of a feedback loop where we may try something and it has or doesn’t have the intended effect. That teaches us more about what’s going on in the body. So, we refine our understanding and then move forward with the best treatment options.
The maintenance phase is when we really have a more thorough understanding of what’s going on, why it was happening, and what needs to be done to correct that course. Ultimately, at this phase, the patient is empowered with that understanding and can manage the situation themselves. And we’re here to help as needed. At Manhattan Pain Medicine, our goal is to bring clarity to what can feel complex and to develop a treatment plan that’s precise, personalized, and treats the pain at its root source.
Complex pain often involves more than one structure, system, or specialty. Our approach is designed to organize that complexity, identify the most important drivers, and guide care in the right sequence. We combine clinical reasoning, precise diagnostics, multi-specialty collaboration, and patient education so treatment is based on understanding, not guesswork.
Explore the Zones of Expertise by clicking or tapping on a circle.
Discovery, Treatment, and Maintenance are not isolated steps. In complex pain, the process is often iterative. A diagnostic block, medication trial, procedure, physical therapy response, or flare pattern may teach us something new and help guide the next decision.
Many patients with complex pain have already tried multiple treatments. Discovery helps reduce unnecessary repetition by asking a more precise question: what is driving the pain, and what should be treated first?
In complex pain, doing the right treatment in the wrong order can lead to frustration or flares. We work to determine what needs to be calmed, repaired, retrained, or monitored first so the treatment plan is more coherent and more tolerable.
Long-term progress depends on more than reducing symptoms. Maintenance helps patients understand their patterns, protect functional gains, manage future flares, and build a life that is no longer organized around pain.
Founder and Medical Director of Manhattan Pain Medicine, triple board-certified in Physical Medicine and Rehabilitation, Pain Medicine, and Headache Medicine.
Board-certified rheumatologist and internal medicine physician specializing in autoimmune, inflammatory, dysautonomia-related, and complex pain conditions.
Fellowship-trained Interventional Pain Management specialist focused on complex chronic pain, autoimmune-related pain, hypermobility, spine pain, nerve pain, and joint pain.
Board-certified Physical Medicine and Rehabilitation specialist focused on pelvic pain, pelvic floor dysfunction, chronic pain, and sexual wellness.
Health and Pain Psychologist integrating psychology, mind-body care, acupuncture, and nervous system regulation for complex chronic pain.
Board-certified Physician Assistant specializing in orthopedic and spine care, clinical intake, and diagnosis-first pain evaluation.
Board-certified Physician Assistant specializing in rheumatology, neurology, headache, autoimmune, and complex pain care.
I cannot say enough good things about Manhattan Pain Medicine. From the moment I walked in, I felt truly cared for and taken seriously. Dr. Nino Mikaberidze, Director of Rheumatology, is exceptional — knowledgeable, compassionate, and incredibly thorough. She takes the time to listen, explains every...
The best care I've received as a chronic pain patient. I traveled from out of state to visit Manhattan Pain Medicine because I could not find knowledgeable doctors in my hometown for my hypermobility, and Ehlers-Danlos syndrome symptoms and comorbidities. Let me tell you, it was worth every travel e...
I was injured in a bicycle accident over 8 years ago. I’ve suffered throughout the years since my accident with nothing seeming to work. PT, Yoga, lifestyle changes, NOTHNG! I finally made an appointment with Dr Kane and I’m feeling an improvement in my life. I no longer stay up all night in pain, a...
One of the best experiences, if not the best, I have ever had at the doctor’s office. From the front desk to the nurses to the PA assisting the doctor this was a great experience. Dr.Nino actually listened to me and came up with a game plan. Would recommend this practice to as many people as I could...
I have very unique & severe nerve pain from CRPS which has no known specific cure. Dr. Siefferman has a huge tool box, far greater than the other 23 Drs. I have seen. He saved me from jumping off a bridge and continues to help me with both treatments and advice. Dr. S. is in a different league!
After two years of searching and feeling lost and let down, I finally found real help at Manhattan Pain Medicine. With Dr. Siefferman, Adam Rosenberg, Dr. Mikaberidze, and the whole team, I feel heard, supported and understood. Every symptom is being considered and I’m finally getting answers with m...
Why is Dr Dr. Tayyaba Ahmed one of the top pevic Floor specialists - 1- She wants to know a full history of what led the patient to get to this point. 2 - She listens intensley to the patient 3- She does not rush you 4- Extremely skilled at giving pelvic floor injections 5- I thank my luck stars she...
The staff was friendly and helpful. Dr. Siefferman was thoughtful, listened, asked questions and proposed simple safe ways to come to further conclusions regarding my pain and discomfort. The office staff including Dr. Siefferman is responsive even after the initial in-person visit. Very pleased.
Dr. Siefferman is a brilliant provider. While my pain is still a work in progress, Dr Siefferman always gives me options and explains his reasoning behind things. He listens to my feedback and concerns. I never feel rushed; and am grateful he works to meet me where I am. I highly recommend him.
What a great find! They listen to me, I listen to them and the diagnosis is made and a plan developed to develop an approach to treat all of my chronic pain. I wish I could have discovered this type of treatment sooner. This doctor and group give me hope.
Before care begins, our team helps patients understand the practical side of treatment, including insurance verification, out-of-network benefits, cost-share estimates, self-pay options, and billing questions. We believe patients should have as much clarity as possible before moving forward.
