Complex Pain Deserves More Than Guesswork

At Manhattan Pain Medicine, we help patients with complex, persistent, or unexplained pain move beyond trial-and-error care. Our diagnosis-first approach looks deeper to understand what is generating the pain, how it developed, and what path forward makes sense.

Pain Is Complex. Care Should Be Precise.

There is rarely one simple explanation for complex pain. Symptoms may involve joints, nerves, muscles, inflammation, connective tissue, the autonomic nervous system, prior injury, medical trauma, or the way the body has learned to protect itself over time.

At Manhattan Pain Medicine, we do not begin with a one-size-fits-all treatment plan. We begin with Discovery. Our team listens carefully, reviews the full history, examines how the body moves and responds, and builds a clinical hypothesis before recommending the next step.

But precision does not mean losing sight of the person. We treat the patient behind the pain: their story, their function, their fears, their goals, and the life they are trying to return to.

The goal is not only to reduce pain, but to understand it, and to help each patient move forward with greater clarity, confidence, and support.

Pain Is Complex. Care Should Be Precise.
ZONES OF EXPERTISE

Expertise Built for Complex Pain

Manhattan Pain Medicine’s Zones of Expertise reflect the focused clinical experience, pattern recognition, and collaborative care our team has developed in treating complex pain. Each zone gives patients a clearer starting point while helping our team evaluate overlapping symptoms, identify underlying drivers, and guide care with greater precision.

Explore the Zones of Expertise by clicking or tapping on a circle.

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HOW WE WORK WITH YOU

A Thoughtful, Personalized Path Through Pain

Care at Manhattan Pain Medicine typically unfolds through three connected phases: Discovery, Treatment, and Maintenance. Each phase is designed to bring more clarity, improve comfort and function, and support long-term progress.

Discovery

We begin by understanding the full pain pattern. Discovery may include history review, physical examination, imaging review, dynamic assessment, symptom tracking, medication trials, or diagnostic blocks to help identify what is generating the pain and what should be addressed first.

Treatment

Treatment is guided by what Discovery reveals. We may combine targeted procedures, regenerative medicine, rheumatologic care, rehabilitation, pain psychology, medication strategy, or coordinated specialty referrals, depending on what is driving the symptoms.

Maintenance

Maintenance focuses on keeping progress stable. Patients build body literacy, learn how to recognize flare patterns, protect functional gains, and move forward with a plan that is no longer based on trial and error.

Why the First Step Matters

Many patients come to Manhattan Pain Medicine after years of partial answers, repeated treatments, or symptoms that do not fit neatly into one diagnosis. The first step is to slow the process down enough to understand what the body is trying to communicate.

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MEET THE TEAM

Care That’s Personal. Expertise That’s Shared.

Complex pain requires more than one perspective. Our physicians and clinical team work within a shared framework, bringing together interventional pain medicine, rheumatology, rehabilitation, pain psychology, regenerative medicine, and trusted partners when needed.

A Team Built Around Complex Pain

At Manhattan Pain Medicine, providers collaborate across specialties to understand the full pattern behind the pain. The goal is not to pass patients from one silo to another, but to bring the right perspectives together around the same clinical question.

Meet Our Team

PATIENT STORIES

Real Patients. Real Progress.

Hear from patients who came to Manhattan Pain Medicine looking for answers, clarity, and a more thoughtful path forward.
  • Madaline. M

    5 star review

    I cannot say enough good things about Manhattan Pain Medicine. From the moment I walked in, I felt truly cared for and taken seriously. Dr. Nino Mikaberidze, Director of Rheumatology, is exceptional — knowledgeable, compassionate, and incredibly thorough. She takes the time to listen, explains every...

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  • Haleigh Y.

    5 star review

    The best care I've received as a chronic pain patient. I traveled from out of state to visit Manhattan Pain Medicine because I could not find knowledgeable doctors in my hometown for my hypermobility, and Ehlers-Danlos syndrome symptoms and comorbidities. Let me tell you, it was worth every travel e...

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  • Damien P.

    5 star review

    I was injured in a bicycle accident over 8 years ago. I’ve suffered throughout the years since my accident with nothing seeming to work. PT, Yoga, lifestyle changes, NOTHNG! I finally made an appointment with Dr Kane and I’m feeling an improvement in my life. I no longer stay up all night in pain, a...

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  • JP S.

    5 star review

    One of the best experiences, if not the best, I have ever had at the doctor’s office. From the front desk to the nurses to the PA assisting the doctor this was a great experience. Dr.Nino actually listened to me and came up with a game plan. Would recommend this practice to as many people as I could...

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  • Richard B.

    5 star review

    I have very unique & severe nerve pain from CRPS which has no known specific cure. Dr. Siefferman has a huge tool box, far greater than the other 23 Drs. I have seen. He saved me from jumping off a bridge and continues to help me with both treatments and advice. Dr. S. is in a different league!

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  • Clare F.

    5 star review

    After two years of searching and feeling lost and let down, I finally found real help at Manhattan Pain Medicine. With Dr. Siefferman, Adam Rosenberg, Dr. Mikaberidze, and the whole team, I feel heard, supported and understood. Every symptom is being considered and I’m finally getting answers with m...

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  • Jonathan C.

    5 star review

    Why is Dr Dr. Tayyaba Ahmed one of the top pevic Floor specialists - 1- She wants to know a full history of what led the patient to get to this point. 2 - She listens intensley to the patient 3- She does not rush you 4- Extremely skilled at giving pelvic floor injections 5- I thank my luck stars she...

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  • Jodi K.

    5 star review

    The staff was friendly and helpful. Dr. Siefferman was thoughtful, listened, asked questions and proposed simple safe ways to come to further conclusions regarding my pain and discomfort. The office staff including Dr. Siefferman is responsive even after the initial in-person visit. Very pleased.

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  • Sabrina S.

    5 star review

    Dr. Siefferman is a brilliant provider. While my pain is still a work in progress, Dr Siefferman always gives me options and explains his reasoning behind things. He listens to my feedback and concerns. I never feel rushed; and am grateful he works to meet me where I am. I highly recommend him.

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  • Lorraine B.

    5 star review

    What a great find! They listen to me, I listen to them and the diagnosis is made and a plan developed to develop an approach to treat all of my chronic pain. I wish I could have discovered this type of treatment sooner. This doctor and group give me hope.

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OUR CLINICAL FOCUS

Some of the Conditions We Commonly Treat

Pain shows up in many different ways, and no two patients experience it the same way. Manhattan Pain Medicine treats a wide range of pain conditions, from localized musculoskeletal pain to complex, long-term pain patterns with more than one contributing factor.

Insights & Research

Explore MPM Insights and Research, including patient-friendly articles, clinical perspectives, and research from our team to help explain how we understand complex pain, evaluate care options, and guide the path to treatment

Understanding Insurance Before You Begin

Before care begins, our team helps patients understand the practical side of treatment, including insurance verification, out-of-network benefits, cost-share estimates, self-pay options, and billing questions. We believe patients should have as much clarity as possible before moving forward.

Insurance & Billing

Pain Care That Starts With Understanding

When pain is complex, the first step should not be another generic treatment. Manhattan Pain Medicine looks deeper to understand what is driving the pain, why it has persisted, and what path forward makes sense for you.

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