At Manhattan Pain Medicine, pain is evaluated before it is treated. Our approach is diagnosis-first and discovery-led, designed to understand what is generating the pain, how it developed, and why it has not resolved. Care is organized through three connected phases: Discovery, Treatment, and Maintenance.
Learn how Dr. Siefferman approaches pain diagnosis and treatment through a personalized, step-by-step process focused on identifying the root cause, reducing pain, and helping patients achieve lasting relief.
Our team organizes conditions and treatments into related zones of expertise to make it easier to explore the care paths most relevant to your symptoms and goals.
Use the zone tags above to browse dedicated pages for each focus area, including services, providers, and what to expect during treatment.
Hi, I’m Dr. Jason Siefferman and I would like to speak to you about our approach to pain diagnosis and treatment at Manhattan Pain Medicine. At its core, pain is a signal. When it’s new, it’s pretty straightforward. We can identify the reason, treat that, get you better. When it’s been going on for some period of time, that’s when the complexity develops. At that point, patients aren’t just dealing with the original issue anymore. There’s often compensatory patterns that have developed, changes in the nervous system based on how that signal is being processed and then other layers that make the pain feel harder to understand and harder to treat.
Our approach is structured, thoughtful, and collaborative. We need to understand the impacts that it has on the rest of your life because that all filters right back into the experience of pain. Our process typically moves through three phases: discovery, treatment, and maintenance. The discovery phase is where we seek comprehensive, complex, thorough, complete diagnosis. Essentially, we want to understand what’s going on and why.
The next phase is treatment. During the treatment phase, there’s always a little bit of a feedback loop where we may try something and it has or doesn’t have the intended effect. That teaches us more about what’s going on in the body. So, we refine our understanding and then move forward with the best treatment options.
The maintenance phase is when we really have a more thorough understanding of what’s going on, why it was happening, and what needs to be done to correct that course. Ultimately, at this phase, the patient is empowered with that understanding and can manage the situation themselves. And we’re here to help as needed. At Manhattan Pain Medicine, our goal is to bring clarity to what can feel complex and to develop a treatment plan that’s precise, personalized, and treats the pain at its root source.
Complex pain often involves more than one structure, system, or specialty. Our approach is designed to organize that complexity, identify the most important drivers, and guide care in the right sequence. We combine clinical reasoning, precise diagnostics, multi-specialty collaboration, and patient education so treatment is based on understanding, not guesswork.
Explore the Zones of Expertise by clicking or tapping on a circle.
Discovery, Treatment, and Maintenance are not isolated steps. In complex pain, the process is often iterative. A diagnostic block, medication trial, procedure, physical therapy response, or flare pattern may teach us something new and help guide the next decision.
Many patients with complex pain have already tried multiple treatments. Discovery helps reduce unnecessary repetition by asking a more precise question: what is driving the pain, and what should be treated first?
In complex pain, doing the right treatment in the wrong order can lead to frustration or flares. We work to determine what needs to be calmed, repaired, retrained, or monitored first so the treatment plan is more coherent and more tolerable.
Long-term progress depends on more than reducing symptoms. Maintenance helps patients understand their patterns, protect functional gains, manage future flares, and build a life that is no longer organized around pain.
Founder and Medical Director of Manhattan Pain Medicine, triple board-certified in Physical Medicine and Rehabilitation, Pain Medicine, and Headache Medicine.
Board-certified rheumatologist and internal medicine physician specializing in autoimmune, inflammatory, dysautonomia-related, and complex pain conditions.
Fellowship-trained Interventional Pain Management specialist focused on complex chronic pain, autoimmune-related pain, hypermobility, spine pain, nerve pain, and joint pain.
Board-certified Physical Medicine and Rehabilitation specialist focused on pelvic pain, pelvic floor dysfunction, chronic pain, and sexual wellness.
Health and Pain Psychologist integrating psychology, mind-body care, acupuncture, and nervous system regulation for complex chronic pain.
Board-certified Physician Assistant specializing in orthopedic and spine care, clinical intake, and diagnosis-first pain evaluation.
Board-certified Physician Assistant specializing in rheumatology, neurology, headache, autoimmune, and complex pain care.
These guys are the best. I've been going here for over 6 years and their familiarity with my Schwannomatosis (most ppl have never even heard of it - its rather rare) and their ability to diagnose my CRPS quickly and accurately and then treat it like I was merely getting a flu shot is just incredible...
Highly recommended for those who need Pain Management. Everyone at Manhattan Pain Medicine is extremely nice and helpful. I have had very good interactions with both Dr. Siefferman and Dr. Louis. All of the staff is very responsive. 5 stars.
The providers at Manhattan Pain Medicine are exceptional. I wish I had found them 30 years ago!
I genuinely can’t say enough good things about the team at Manhattan Pain Medicine. I have MCAS, EDS, and an inflammatory autoimmune disease, and I’ve basically been searching for answers since I was a kid. I had years of unexplained inflammation markers, chronic pain, and allergic reactions despite...
I have a complex medical history and have seen a lot of doctors over the years. Dr. Mikaberidze and Dr. Siefferman each took the time to really listen and understand everything I had been dealing with. I also appreciated how they work together and communicated about my care. I left with a plan that...
Sharing my gratitude for the pleasant experience last week during my visit, the medical team provided great care and also treated my session as a learning experience, I left my session with a wealth of knowledge. A big thank you to the kind, and professional staff who welcomed me to the office as a...
I cannot say enough good things about Manhattan Pain Medicine. From the moment I walked in, I felt truly cared for and taken seriously. Dr. Nino Mikaberidze, Director of Rheumatology, is exceptional — knowledgeable, compassionate, and incredibly thorough. She takes the time to listen, explains every...
Dr Siefferman is the most thorough, patient doctor I have even been to. Currently I travel from miami to nyc to see him because his bed side manner and desire to help is incomparable.
ZocDoc
This practice is wonderful. I have been a patient of Dr. Siefferman’s since 2019 and he’s extremely helpful and kind. He has brought in a Rheumatologist who is also great. They handle very complex pain issues and always try to find new ways to help me.
Dr. Siefferman is an incredible doctor! He is extremely diligent and knowledgeable. It feels like you are his only patient. He invests a lot of time and effort into your injuries and concerns. I did not find these wonderful qualities with other pain specialists before, who were always rushed and som...
ZocDoc
Dr. Siefferman is a doctor who combines the old world bedside manner of doctors from my childhood (60 years ago) with a sta te of the art embrace of modern technology. It is always a pleasure to have an appointment with him...always has options and solutions to my medical issues. He is truly the doc...
ZocDoc
Dr. Siefferman is a genius. He is very informed and listens attentively.
ZocDoc
Dr. Siefferman and his entire team continue to be efficient, dedicated, and driven by precision and a genuine desire to give fantastic care. Will always recommend.
ZocDoc
Doctor Siefferman is fantastic. Have been seeing him for 5 years. Couldn’t recommend more.
ZocDoc
Dr. Siefferman is the ONLY doctor who has ever been able to diagnose my pain and treat it. He is hands down the best
ZocDoc
Before care begins, our team helps patients understand the practical side of treatment, including insurance verification, out-of-network benefits, cost-share estimates, self-pay options, and billing questions. We believe patients should have as much clarity as possible before moving forward.
