C1/2 facet injections may help evaluate or temporarily reduce selected upper cervical pain, headache overlap, or suspected CCI-related pain patterns.
Craniocervical instability can contribute to chronic head and neck pain. Dr. Siefferman discusses C1/C2 facet injections, how they may help diagnose and treat pain, and when they may be an appropriate option.
Our team organizes conditions and treatments into related zones of expertise to make it easier to explore the care paths most relevant to your symptoms and goals.
Use the zone tags above to browse dedicated pages for each focus area, including services, providers, and what to expect during treatment.
Hi, I’m Dr. Jason Siefferman, an interventional pain specialist and medical director at Manhattan Pain Medicine. Craniocervical instability either occurs where the occiput joins C1 or where C1 joins C2, and there is hypermobility at either or both of those levels.
If we suspect craniocervical instability, of course, we go through the diagnostic workup process of getting dynamic X-rays and trialing a cervical collar. If both of these things are consistent and the patient’s story is consistent with craniocervical instability, then we will discuss a diagnostic injection at C1-C2. We will use the injection at C1-C2 to distinguish where the symptoms are coming from.
If the cervical collar treats both the C0-C1 and the C1-C2, and we know the injection only covers C1-C2, that helps us establish what symptoms are coming from C1-C2 versus C0-C1 by subtraction. We also offer regenerative medicine injections. We can use prolotherapy, and we can use platelet-rich plasma at the C1-C2 level if it is diagnostically helpful. And many patients do find good relief with this approach.
C1/2 facet injections are highly specialized upper cervical procedures that target the C1-C2 facet joint, also called the lateral atlantoaxial joint. This joint sits high in the neck between the first and second cervical vertebrae and may contribute to selected patterns of upper neck pain, headache, and craniocervical pain.
At Manhattan Pain Medicine, C1 C2 facet injection NYC care begins with diagnosis-first evaluation. The goal is to determine whether the C1-C2 joint is likely contributing to symptoms or whether pain may be coming from migraine, occipital neuralgia, muscle guarding, Chiari malformation, intracranial pressure concerns, CSF flow issues, jugular stenosis, tethered cord, instability, nerve irritation, or another condition. These injections do not diagnose or cure CCI by themselves, but they may provide useful diagnostic information and temporary relief in carefully selected patients.
MPM specialists evaluate whether a C1/2 facet injection may be appropriate by reviewing the patient’s upper neck pain pattern, headache symptoms, instability concerns, hypermobility history, EDS diagnosis, prior imaging, neurological symptoms, prior injections, bracing response, physical therapy history, medication response, and safety factors. Upper cervical pain can overlap with craniocervical instability, atlantoaxial joint irritation, muscle guarding, occipital nerve irritation, migraine, cervicogenic headache, Chiari-related anatomy, intracranial hypertension, CSF outflow obstruction, jugular stenosis, tethered cord, and central sensitization.
MPM carefully reviews these possibilities before determining whether a C1/2 facet injection, occipital nerve block, trigger point injection, prolotherapy, PRP, regenerative medicine, physical therapy, bracing, neurology evaluation, neurosurgical review, or another pathway may be appropriate.
Patients often search for C1 C2 facet injection in Manhattan when they have upper neck pain, headache, hypermobility-related neck symptoms, EDS, suspected CCI, or pain that has not improved enough with physical therapy, bracing, medication, nerve blocks, imaging-based evaluation, or specialist care.
MPM approaches C1/2 facet injections as specialized diagnostic and therapeutic tools, not as general neck injections or CCI cures. In selected patients, temporary relief after a C1/2 injection may suggest that the upper cervical facet joint is contributing to pain. If the response is limited or absent, the care team may reassess whether another pain generator is more likely. This is especially important in complex patients with overlapping neurological, structural, headache, hypermobility, and connective tissue concerns.
C1/2 facet injections fit within MPM’s Complex Chronic Pain, Musculoskeletal issues, Hypermobility, and Headache expertise because upper cervical pain often involves overlapping structures and systems. Patients with EDS or hypermobility spectrum disorder may have joint instability, muscle guarding, headache overlap, nerve sensitivity, and complex symptom patterns that require careful evaluation.
MPM uses C1/2 facet injections as part of a broader diagnostic and treatment framework. The injection may provide useful information and temporary relief, but it is not a standalone answer for CCI, EDS, Chiari malformation, intracranial hypertension, jugular stenosis, tethered cord, or complex headache disorders. Treatment planning may also include physical therapy, bracing guidance, medication management, occipital nerve blocks, trigger point injections, regenerative medicine, prolotherapy, PRP, neurology review, neurosurgical evaluation, or other coordinated care when appropriate.
Before a C1/2 facet injection, MPM reviews the suspected pain generator, imaging, anatomy, medication history, allergies, bleeding risk, neurological symptoms, procedural risks, alternatives, and post-procedure instructions. The injection is directed toward the C1-C2 facet joint or lateral atlantoaxial joint region. Because this area is close to critical structures, image guidance and careful procedural planning are essential.
Patients may feel pressure, brief discomfort, temporary numbness, soreness, dizziness, headache flare, or a short pain flare after the injection. Relief may occur quickly if local anesthetic is used, while steroid-related relief, when used, may take longer. Some patients experience temporary improvement, some have longer benefit, and some do not respond. MPM reviews the response to determine whether the C1-C2 joint appears clinically meaningful and what next step is appropriate.
These guys are the best. I've been going here for over 6 years and their familiarity with my Schwannomatosis (most ppl have never even heard of it - its rather rare) and their ability to diagnose my CRPS quickly and accurately and then treat it like I was merely getting a flu shot is just incredible...
Highly recommended for those who need Pain Management. Everyone at Manhattan Pain Medicine is extremely nice and helpful. I have had very good interactions with both Dr. Siefferman and Dr. Louis. All of the staff is very responsive. 5 stars.
The providers at Manhattan Pain Medicine are exceptional. I wish I had found them 30 years ago!
I genuinely can’t say enough good things about the team at Manhattan Pain Medicine. I have MCAS, EDS, and an inflammatory autoimmune disease, and I’ve basically been searching for answers since I was a kid. I had years of unexplained inflammation markers, chronic pain, and allergic reactions despite...
I have a complex medical history and have seen a lot of doctors over the years. Dr. Mikaberidze and Dr. Siefferman each took the time to really listen and understand everything I had been dealing with. I also appreciated how they work together and communicated about my care. I left with a plan that...
Sharing my gratitude for the pleasant experience last week during my visit, the medical team provided great care and also treated my session as a learning experience, I left my session with a wealth of knowledge. A big thank you to the kind, and professional staff who welcomed me to the office as a...
I cannot say enough good things about Manhattan Pain Medicine. From the moment I walked in, I felt truly cared for and taken seriously. Dr. Nino Mikaberidze, Director of Rheumatology, is exceptional — knowledgeable, compassionate, and incredibly thorough. She takes the time to listen, explains every...
Dr Siefferman is the most thorough, patient doctor I have even been to. Currently I travel from miami to nyc to see him because his bed side manner and desire to help is incomparable.
ZocDoc
This practice is wonderful. I have been a patient of Dr. Siefferman’s since 2019 and he’s extremely helpful and kind. He has brought in a Rheumatologist who is also great. They handle very complex pain issues and always try to find new ways to help me.
Dr. Siefferman is an incredible doctor! He is extremely diligent and knowledgeable. It feels like you are his only patient. He invests a lot of time and effort into your injuries and concerns. I did not find these wonderful qualities with other pain specialists before, who were always rushed and som...
ZocDoc
Dr. Siefferman is a doctor who combines the old world bedside manner of doctors from my childhood (60 years ago) with a sta te of the art embrace of modern technology. It is always a pleasure to have an appointment with him...always has options and solutions to my medical issues. He is truly the doc...
ZocDoc
Dr. Siefferman is a genius. He is very informed and listens attentively.
ZocDoc
Dr. Siefferman and his entire team continue to be efficient, dedicated, and driven by precision and a genuine desire to give fantastic care. Will always recommend.
ZocDoc
Doctor Siefferman is fantastic. Have been seeing him for 5 years. Couldn’t recommend more.
ZocDoc
Dr. Siefferman is the ONLY doctor who has ever been able to diagnose my pain and treat it. He is hands down the best
ZocDoc
A C1/2 facet injection is a targeted upper cervical injection directed toward the C1-C2 facet joint, also called the lateral atlantoaxial joint. This joint sits between the first and second cervical vertebrae. The injection may be used to evaluate whether the joint is contributing to upper neck pain, headache overlap, or suspected CCI-related pain patterns. It may also provide temporary relief in selected patients.
The C1-C2 joint is the joint between the atlas, which is the first cervical vertebra, and the axis, which is the second cervical vertebra. It plays an important role in upper neck rotation and skull-neck mechanics. Because of its location near important nerves, blood vessels, and the spinal canal, procedures in this area require careful anatomical review and image-guided planning.
C1/2 facet injections may help selected patients when the C1-C2 joint is suspected to contribute to pain in the setting of CCI, hypermobility, or upper cervical symptoms. The injection does not cure CCI or stabilize the neck. It may provide temporary relief or diagnostic information that helps clarify whether the C1-C2 joint is a meaningful pain generator.
C1/2 facet injections may help selected patients with upper neck pain or headache overlap when symptoms suggest involvement of the C1-C2 joint. However, headache and upper neck pain can also come from migraine, occipital neuralgia, muscle guarding, Chiari malformation, intracranial pressure disorders, CSF flow concerns, cervical spine disease, or other causes. MPM evaluates these possibilities before recommending treatment.
C1/2 facet injections may be considered in selected patients with EDS or hypermobility when the C1-C2 joint appears to be a meaningful pain generator. The injection does not treat the underlying connective tissue condition or correct instability. It may help clarify whether the upper cervical joint is contributing to symptoms and may provide temporary relief as part of a broader plan.
C1/2 facet injections may be diagnostic, therapeutic, or both. A diagnostic injection helps determine whether the C1-C2 joint is contributing to pain. A therapeutic injection is intended to reduce pain for a period of time. Relief may be temporary, but the pattern of relief can still help guide next steps in care.
A C1/2 facet injection targets the upper cervical joint between the first and second vertebrae. An occipital nerve block targets the greater or lesser occipital nerves, which may contribute to pain at the back of the head or scalp. These pain patterns can overlap. MPM determines which target is more appropriate based on symptoms, exam findings, imaging, and prior response to treatment.
A C1/2 facet injection usually targets the joint to help evaluate or reduce pain from that area. Prolotherapy is a regenerative injection technique that may be considered for selected ligament, tendon, joint, or instability-related pain patterns. In the upper cervical region, patient selection and safety planning are especially important. MPM evaluates whether diagnostic injection, prolotherapy, PRP, regenerative medicine, or specialist referral is most appropriate.
Craniocervical instability is diagnosed through a combination of clinical history, physical findings, imaging, and specialist interpretation. Symptoms alone are not enough, and imaging alone may not explain the full clinical picture. Evaluation may involve neurology, neurosurgery, spine specialists, radiology review, and assessment for related conditions such as EDS, Chiari malformation, intracranial pressure concerns, CSF flow issues, or tethered cord.
No. C1/2 facet injections do not diagnose CCI by themselves. They may help determine whether the C1-C2 joint is contributing to pain, but they do not prove or rule out craniocervical instability. CCI diagnosis requires appropriate clinical and imaging evaluation, often with specialist involvement when structural instability or neurological symptoms are suspected.
Imaging needs vary by patient. MPM reviews relevant prior imaging and may recommend additional imaging or specialist review when anatomy, instability, vascular structures, neurological symptoms, Chiari-related concerns, intracranial pressure issues, CSF flow concerns, or other safety factors need clarification. Because the C1-C2 region is technically sensitive, imaging review is an important part of procedural planning.
Yes, C1/2 facet injections require careful image-guided planning because the region is close to critical structures, including the vertebral artery, spinal canal, nerve structures, and upper cervical anatomy. Image guidance helps support accurate placement and procedural safety, but it does not guarantee relief. MPM determines the safest and most appropriate approach based on anatomy and clinical context.
Temporary relief may suggest that the C1-C2 joint is contributing to the patient’s pain pattern. The timing, degree, and location of relief matter. If relief occurs in the expected area, MPM may use that information to guide future care. If relief is limited, absent, or does not match the expected pattern, another pain generator may need to be considered.
Risks may include pain flare, headache flare, bruising, bleeding, infection, allergic reaction, temporary numbness or weakness, dizziness, vasovagal reaction, steroid-related side effects when steroids are used, vascular injury, vertebral artery injury, nerve irritation, spinal cord or thecal sac injury, local anesthetic toxicity, incomplete relief, temporary relief only, or no relief. Sudden severe headache, new neurological deficits, vision loss, difficulty speaking, difficulty swallowing, fainting, severe dizziness, loss of coordination, fever, severe neck pain after trauma, signs of stroke, or rapidly worsening symptoms require urgent evaluation.
C1/2 facet injections may not be appropriate when symptoms are better explained by another condition, when the pain generator is unclear, when imaging or anatomy raises safety concerns, or when urgent neurological, vascular, surgical, or emergency evaluation is needed. They may also be delayed or avoided when there is active infection, uncontrolled bleeding risk, medication concerns, unstable medical conditions, or severe red flag symptoms.
Before care begins, our team helps patients understand the practical side of treatment, including insurance verification, out-of-network benefits, cost-share estimates, self-pay options, and billing questions. We believe patients should have as much clarity as possible before moving forward.
If you are considering a C1 C2 facet injection in NYC for upper neck pain, headache overlap, suspected CCI-related pain, hypermobility, EDS-related cervical symptoms, or complex craniocervical pain, MPM can help determine whether this procedure may be appropriate. Your evaluation will consider your symptoms, imaging, anatomy, prior care, safety factors, and treatment goals before any recommendation is made.
C1/2 facet injections are specialized upper cervical procedures directed toward the C1-C2 facet joint, also called the lateral atlantoaxial joint. This joint sits high in the neck between the atlas and axis, the first two cervical vertebrae. It plays an important role in upper cervical rotation and skull-neck mechanics.
At Manhattan Pain Medicine (MPM), C1 C2 facet injection NYC care begins with diagnosis-first evaluation. The goal is to determine whether pain is coming from the C1-C2 joint or whether symptoms may be better explained by another upper cervical, neurological, headache, vascular, structural, or connective tissue-related condition.
The C1-C2 joint is different from many other spinal joints because of its location, motion, and nearby anatomy. It can be involved in selected cases of upper neck pain, skull base pain, headache overlap, pain with rotation, and suspected atlantoaxial joint-mediated pain.
In patients with hypermobility or EDS, upper cervical pain may be more complex. Symptoms may involve joint laxity, muscle guarding, altered mechanics, headache disorders, nerve irritation, or broader craniocervical concerns. A C1/2 facet injection may help clarify whether the C1-C2 joint is contributing to the pain pattern, but it does not diagnose or cure CCI.
Craniocervical instability can involve complex structural and neurological considerations. Patients may describe upper neck pain, headache, dizziness, instability sensations, visual symptoms, neurological complaints, or symptoms that worsen with certain positions. These symptoms can overlap with migraine, occipital neuralgia, Chiari malformation, intracranial hypertension, CSF outflow obstruction, jugular stenosis, tethered cord, cervical spine disease, and central sensitization.
MPM evaluates whether the patient’s symptoms and imaging suggest a C1-C2 joint pain generator. If the joint appears clinically relevant and the procedure can be performed safely, a C1/2 facet injection may be considered as part of the diagnostic and treatment plan.
A C1/2 facet injection may provide temporary relief when the C1-C2 joint is contributing to pain. It may also provide diagnostic information. For example, if the injection reduces the patient’s usual upper neck pain or headache pattern for a period of time, that response may support the C1-C2 joint as part of the pain picture.
The injection cannot stabilize the neck, correct ligament laxity, reverse hypermobility, treat Chiari malformation, correct CSF flow issues, resolve intracranial hypertension, treat jugular stenosis, or diagnose tethered cord. It is one tool that may help clarify the role of the C1-C2 joint in selected patients.
C1-C2 injections are technically sensitive because the region is close to critical structures, including the vertebral artery, thecal sac, spinal cord, C2 dorsal root ganglion, and upper cervical nerves. Preprocedural imaging review and careful image-guided planning are important.
MPM reviews anatomy, prior imaging, neurological symptoms, medication history, bleeding risk, allergy history, prior procedures, and red flags before determining whether a C1/2 facet injection is appropriate. If symptoms suggest neurological compromise, vascular involvement, structural instability requiring specialist review, or an urgent condition, MPM may recommend additional evaluation before any injection is considered.
A C1/2 facet injection targets the upper cervical joint. An occipital nerve block targets nerves that may contribute to pain at the back of the head or scalp. Trigger point injections target painful muscle bands that may contribute to neck, shoulder, or headache-related pain. Prolotherapy or PRP may be considered in selected cases when a regenerative approach is clinically appropriate for certain joint, ligament, or instability-related pain patterns.
These treatments are not interchangeable. MPM determines the best pathway by matching symptoms, exam findings, imaging, and prior response to the suspected pain generator.
Relief after a C1/2 facet injection can be informative. If the patient’s usual pain improves in the expected location and timeframe, the C1-C2 joint may be contributing to symptoms. If the relief is short-lived, that information may still help guide treatment planning.
If the injection does not help, that does not mean the symptoms are not real. It may mean the C1-C2 joint is not the primary pain generator, the pain is coming from another structure, or the condition requires a different diagnostic pathway. MPM uses the response to refine the plan rather than assuming one procedure can answer every question.
Patients with suspected CCI, EDS, hypermobility, Chiari malformation, intracranial pressure concerns, CSF flow issues, jugular stenosis, tethered cord, or complex headache overlap often need coordinated care. Depending on the clinical picture, MPM may coordinate with neurology, neurosurgery, spine surgery, radiology, physical therapy, regenerative medicine, headache care, pain psychology, or other specialists.
The goal is not simply to inject the upper neck. The goal is to determine whether the C1-C2 joint is a meaningful pain generator and how that information fits into a broader, medically responsible plan.
Risks may include pain flare, headache flare, bruising, bleeding, infection, allergic reaction, temporary numbness or weakness, dizziness, vasovagal reaction, steroid-related side effects when steroids are used, vascular injury, vertebral artery injury, nerve irritation, spinal cord or thecal sac injury, local anesthetic toxicity, incomplete relief, temporary relief only, or no relief.
Patients should seek urgent evaluation for sudden severe headache, new neurological deficits, weakness, numbness, vision loss, difficulty speaking, difficulty swallowing, fainting, severe dizziness, loss of coordination, bowel or bladder dysfunction, fever, severe neck pain after trauma, rapidly worsening headache or neck pain, chest pain, shortness of breath, severe allergic reaction, or signs of stroke.
For selected patients, a C1/2 facet injection may be an important step in understanding upper cervical pain and suspected CCI-related pain patterns. MPM’s role is to determine whether the C1-C2 joint is clinically relevant, whether the procedure can be performed safely, and how the injection fits within a coordinated care plan.
