Chronic Migraine Evaluation and Treatment in Manhattan

Chronic migraine can cause headache on many days of the month, often with nausea, light sensitivity, sound sensitivity, dizziness, neck pain, facial pain, autonomic symptoms, or significant disruption to daily life.

Related Zones of Expertise

Chronic migraines can disrupt every aspect of daily life. Dr. Siefferman explains how migraines are diagnosed and the personalized treatment options available to reduce their frequency, severity, and impact.

Understanding Chronic Migraine

Chronic migraine is a high-frequency neurological pain condition that can affect daily function, work, sleep, concentration, movement, and quality of life. It is different from occasional migraine because headache occurs on many days of the month and often requires a more coordinated preventive treatment plan.

Chronic migraine is commonly defined as headache occurring on 15 or more days per month for more than three months, with migraine features on at least eight days per month. Migraine features may include throbbing or pulsing pain, nausea, vomiting, light sensitivity, sound sensitivity, aura, dizziness, neck discomfort, facial pain, or worsening with activity.

At Manhattan Pain Medicine (MPM), evaluation begins by confirming the headache pattern and identifying overlapping contributors. These may include autonomic dysfunction, POTS-like symptoms, cervical pain, TMJ dysfunction, dystonia, trigeminal nerve pain, EDS, hypermobility, MCAS, lupus, post-COVID symptoms, medication overuse, sleep disruption, stress physiology, or central sensitization.

Specialist Care for Frequent and Treatment-Resistant Migraine

For patients looking for chronic migraine treatment in Manhattan, MPM evaluates more than headache frequency alone. The assessment may include migraine symptoms, number of headache days per month, medication use, prior preventive therapies, response to Botox or CGRP medications, dizziness, nausea, light sensitivity, neck pain, jaw pain, facial pain, autonomic symptoms, post-COVID changes, inflammatory history, hypermobility, and prior imaging or specialist workup.

Care may include medication management, Botox for chronic migraine in appropriately selected patients, selected nerve blocks, trigger point injections, pain psychology, biofeedback, acupuncture, ketamine-related therapies when appropriate, and coordination with neurology, rheumatology, ENT, dentistry, ophthalmology, neurosurgery, primary care, or other specialists when needed.

MPM does not treat every migraine with procedures. Treatment depends on the headache diagnosis, frequency, medical history, medication pattern, prior response to care, safety considerations, and functional goals.

Why Chronic Migraine Requires Careful Evaluation

Chronic migraine can become difficult to manage when symptoms occur on most days, when acute medications are used frequently, or when the headache pattern overlaps with neck pain, jaw pain, autonomic symptoms, post-viral illness, inflammatory conditions, or chronic pain sensitization.

Some patients have migraine with dizziness, fatigue, rapid heart rate, nausea, light sensitivity, sound sensitivity, facial pain, or neck-related symptoms. Others have headache patterns that overlap with EDS, hypermobility spectrum disorder, POTS, MCAS, lupus, post-COVID pain, cervical dystonia, TMJ disorders, CCI, Chiari malformation, CSF outflow obstruction, or intracranial hypertension.

MPM’s diagnosis-first approach is designed to identify the dominant headache pattern, review medication use, screen for red flags, and determine which treatments or referrals are appropriate.

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Diagnosis-first care

How MPM Approaches Chronic Migraine Evaluation

MPM evaluates chronic migraine by confirming the headache pattern, reviewing medication use, and identifying overlapping nerve, neck, jaw, autonomic, inflammatory, and chronic pain contributors.
  • 1

    Confirm the Headache Pattern

    MPM reviews how many headache days occur each month, how many days include migraine features, how long symptoms have been present, and how the headaches affect function. This helps determine whether the pattern fits chronic migraine or another headache disorder.
  • 2

    Review Medication Use and Prior Treatment

    Frequent use of acute headache medication can contribute to medication overuse headache in some patients. MPM reviews over-the-counter medications, triptans, preventive medications, CGRP therapies, Botox history, infusion history, emergency care, and prior responses to treatment.
  • 3

    Evaluate Overlapping Contributors

    Chronic migraine may overlap with autonomic dysfunction, POTS-like symptoms, cervical pain, TMJ dysfunction, dystonia, trigeminal nerve pain, hypermobility, EDS, MCAS, lupus, post-COVID symptoms, sleep disruption, stress physiology, or central pain sensitization. MPM evaluates these contributors without assuming they explain every migraine.
  • 4

    Build a Coordinated Treatment Plan

    Treatment may include medication management, Botox for chronic migraine, selected nerve blocks, trigger point injections, biofeedback, pain psychology, acupuncture, infusion-based options when appropriate, and coordination with neurology, rheumatology, ENT, dentistry, ophthalmology, neurosurgery, or primary care.

Chronic Migraine, Headache, and Autonomic Dysfunction

Chronic migraine is part of MPM’s Headache Zone of Expertise, with important overlap in Autonomic dysfunction when symptoms include dizziness, rapid heart rate, lightheadedness, nausea, fatigue, temperature sensitivity, GI symptoms, or POTS-like episodes.

For some patients, migraine is primarily driven by headache biology. For others, migraine may coexist with autonomic symptoms, hypermobility, neck pain, jaw pain, post-viral symptoms, inflammatory disease, or chronic pain sensitization.

MPM’s role is to clarify the pattern, identify treatable contributors, and coordinate care when chronic migraine is part of a broader multisystem presentation.

PATIENT STORIES

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Hear from patients who came to Manhattan Pain Medicine looking for answers, clarity, and a more thoughtful path forward.
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    5 star review

    These guys are the best. I've been going here for over 6 years and their familiarity with my Schwannomatosis (most ppl have never even heard of it - its rather rare) and their ability to diagnose my CRPS quickly and accurately and then treat it like I was merely getting a flu shot is just incredible...

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    Highly recommended for those who need Pain Management. Everyone at Manhattan Pain Medicine is extremely nice and helpful. I have had very good interactions with both Dr. Siefferman and Dr. Louis. All of the staff is very responsive. 5 stars.

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    The providers at Manhattan Pain Medicine are exceptional. I wish I had found them 30 years ago!

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  • Annie R.

    5 star review

    I genuinely can’t say enough good things about the team at Manhattan Pain Medicine. I have MCAS, EDS, and an inflammatory autoimmune disease, and I’ve basically been searching for answers since I was a kid. I had years of unexplained inflammation markers, chronic pain, and allergic reactions despite...

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  • Karine S.

    5 star review

    I have a complex medical history and have seen a lot of doctors over the years. Dr. Mikaberidze and Dr. Siefferman each took the time to really listen and understand everything I had been dealing with. I also appreciated how they work together and communicated about my care. I left with a plan that...

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  • Edwin F-S.

    5 star review

    Sharing my gratitude for the pleasant experience last week during my visit, the medical team provided great care and also treated my session as a learning experience, I left my session with a wealth of knowledge. A big thank you to the kind, and professional staff who welcomed me to the office as a...

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  • Madaline. M

    5 star review

    I cannot say enough good things about Manhattan Pain Medicine. From the moment I walked in, I felt truly cared for and taken seriously. Dr. Nino Mikaberidze, Director of Rheumatology, is exceptional — knowledgeable, compassionate, and incredibly thorough. She takes the time to listen, explains every...

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  • Lauren W.

    5 star review

    Dr Siefferman is the most thorough, patient doctor I have even been to. Currently I travel from miami to nyc to see him because his bed side manner and desire to help is incomparable.

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  • Dana S.

    5 star review

    This practice is wonderful. I have been a patient of Dr. Siefferman’s since 2019 and he’s extremely helpful and kind. He has brought in a Rheumatologist who is also great. They handle very complex pain issues and always try to find new ways to help me.

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  • Frans M.

    5 star review

    Dr. Siefferman is an incredible doctor! He is extremely diligent and knowledgeable. It feels like you are his only patient. He invests a lot of time and effort into your injuries and concerns. I did not find these wonderful qualities with other pain specialists before, who were always rushed and som...

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  • Gregory S.

    5 star review

    Dr. Siefferman is a doctor who combines the old world bedside manner of doctors from my childhood (60 years ago) with a sta te of the art embrace of modern technology. It is always a pleasure to have an appointment with him...always has options and solutions to my medical issues. He is truly the doc...

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  • Judith R.

    5 star review

    Dr. Siefferman is a genius. He is very informed and listens attentively.

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  • Joshua M.

    5 star review

    Dr. Siefferman and his entire team continue to be efficient, dedicated, and driven by precision and a genuine desire to give fantastic care. Will always recommend.

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  • Michael W. S

    5 star review

    Doctor Siefferman is fantastic. Have been seeing him for 5 years. Couldn’t recommend more.

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  • Stephanie G.

    5 star review

    Dr. Siefferman is the ONLY doctor who has ever been able to diagnose my pain and treat it. He is hands down the best

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Chronic Migraine FAQs

Related conditions

Conditions That May Overlap With Chronic Migraine

Chronic migraine may overlap with headache and migraine, cluster headache, hemicrania, tension headache, trigeminal autonomic cephalalgia, trigeminal neuralgia, craniocervical instability, CSF outflow obstruction, intracranial hypertension, Chiari malformation, cervical dystonia, orofacial dystonia, TMJ disorders, lupus, MCAS, post-COVID pain, EDS, and hypermobility spectrum disorder.

Understanding Insurance Before You Begin

Before care begins, our team helps patients understand the practical side of treatment, including insurance verification, out-of-network benefits, cost-share estimates, self-pay options, and billing questions. We believe patients should have as much clarity as possible before moving forward.

Insurance & Billing

Request a Chronic Migraine Evaluation

If migraines are happening on many days of the month, interfering with your life, or not responding to standard treatment, MPM can help evaluate what may be contributing. Our diagnosis-first approach considers chronic migraine, medication overuse, neck and jaw contributors, autonomic dysfunction, POTS-like symptoms, hypermobility, post-COVID symptoms, inflammatory overlap, trigeminal nerve pain, and central sensitization. Request an appointment to discuss your symptoms and care options.

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Insights & Research

Explore MPM Insights and Research, including patient-friendly articles, clinical perspectives, and research from our team to help explain how we understand complex pain, evaluate care options, and guide the path to treatment
Patient education

A Deeper Look at Chronic Migraine and Complex Headache Care

Chronic migraine is a frequent headache disorder that often requires preventive care, medication review, and evaluation of overlapping neck, jaw, nerve, autonomic, inflammatory, and chronic pain contributors.

Chronic Migraine

Chronic migraine is more than having “a lot of headaches.” It is a high-frequency neurological pain condition that can affect daily function, concentration, sleep, work, relationships, exercise, and quality of life. Many patients with chronic migraine experience headache on most days, with migraine features such as nausea, light sensitivity, sound sensitivity, dizziness, throbbing pain, aura, neck discomfort, facial pain, or worsening with activity.

Chronic migraine is commonly defined as headache on 15 or more days per month for more than three months, with migraine features on at least eight of those days. This definition matters because chronic migraine is often treated differently from occasional migraine. Patients may need preventive care, medication review, Botox consideration, evaluation for medication overuse, and a broader look at overlapping symptoms.

Why Migraines Can Become Chronic

Migraine can become chronic for many reasons. Some patients have frequent attacks because of migraine biology, genetics, hormonal patterns, sleep disruption, stress physiology, triggers, or changes in routine. Others develop more frequent headaches after illness, injury, COVID infection, medication changes, or periods of increased pain and nervous system sensitivity.

Medication overuse can also contribute. When acute headache medications are used too often, the headache pattern may worsen or become more persistent. This does not mean the patient did anything wrong. It means the medication pattern needs to be reviewed carefully and adjusted under clinician supervision.

MPM evaluates headache frequency, medication use, prior treatment response, and overlapping conditions before recommending a plan.

Chronic Migraine and Autonomic Symptoms

Many migraine patients experience symptoms that involve the autonomic nervous system. These may include dizziness, lightheadedness, nausea, flushing, sweating changes, tearing, nasal congestion, rapid heart rate, temperature sensitivity, GI symptoms, or fatigue.

For some patients, these symptoms are part of the migraine pattern. For others, they may overlap with POTS, dysautonomia, post-COVID symptoms, MCAS-like symptoms, or another autonomic condition. MPM evaluates these symptoms in context and coordinates with cardiology, neurology, primary care, or autonomic specialists when needed.

Chronic Migraine With Neck Pain, TMJ, or Dystonia

Chronic migraine often overlaps with neck pain, jaw pain, muscle tension, or facial pain. Some patients have cervical muscle guarding, trigger points, cervical dystonia, TMJ dysfunction, bruxism, or orofacial dystonia that may contribute to headache intensity or frequency.

This does not mean every migraine comes from the neck or jaw. It means those areas should be evaluated when symptoms suggest overlap. MPM reviews the headache pattern, neck mobility, jaw symptoms, muscle tenderness, dystonia patterns, and nerve-related pain to determine whether targeted treatment may be appropriate.

Chronic Migraine, EDS, CCI, and Hypermobility

Some patients with EDS or hypermobility spectrum disorder report migraine, neck pain, dizziness, jaw symptoms, fatigue, or positional head pressure. In selected cases, headache evaluation may need to consider craniocervical instability, Chiari malformation, CSF outflow obstruction, intracranial hypertension, or other structural or pressure-related concerns.

These conditions require careful review and appropriate specialty coordination. MPM does not assume that hypermobility causes chronic migraine, but it does consider whether connective tissue laxity, cervical mechanics, autonomic symptoms, or pain sensitization may be part of the patient’s overall presentation.

Chronic Migraine After COVID or Inflammatory Illness

Some patients develop new or worsened migraine after COVID or another inflammatory or post-viral illness. Others have migraine flares in the setting of lupus, MCAS-like symptoms, autoimmune disease, or systemic inflammatory symptoms.

MPM evaluates whether the headache pattern appears consistent with chronic migraine alone, post-viral headache, inflammatory overlap, autonomic dysfunction, central sensitization, or another condition. Coordination with neurology, rheumatology, primary care, or other specialists may be needed when systemic symptoms are present.

Treatment Options for Chronic Migraine

Treatment for chronic migraine should be individualized. Options may include medication management, acute medication planning, preventive medications, CGRP-targeting therapies, Botox for chronic migraine, sleep and trigger management, biofeedback, pain psychology, acupuncture, and selected procedures when the pain pattern supports them.

Botox is used preventively for appropriately selected chronic migraine patients. It is not used for every headache type and should be considered only after confirming that the patient’s headache pattern and medical history support it.

Nerve blocks may be considered when headache or facial pain suggests involvement of a specific nerve pathway. Trigger point injections may be considered when muscle pain or myofascial pain contributes to the headache pattern. Ketamine therapy, lidocaine and ketamine infusions, and other infusion-based treatments should be considered only in selected patients and are not standard treatments for every chronic migraine presentation.

Pain Psychology and Biofeedback for Chronic Migraine

Pain psychology and biofeedback can be useful parts of care for some chronic migraine patients. These treatments do not suggest that migraine is imagined. They support nervous system regulation, coping, pacing, sleep, stress physiology, fear of symptoms, and function.

This can be especially helpful when chronic migraine overlaps with medical trauma, central sensitization, autonomic symptoms, anxiety around flares, or long-standing pain.

When Imaging or Specialty Care May Be Needed

Some migraine patients need imaging or additional specialty evaluation, especially when headaches are new, changing, severe, unusual, neurologically complex, or associated with red flags. Neurology, ophthalmology, ENT, dentistry, rheumatology, neurosurgery, or primary care may be involved depending on the symptoms.

MPM coordinates care when chronic migraine overlaps with trigeminal neuralgia, cluster headache, TACs, TMJ disorders, cervical dystonia, CCI, Chiari malformation, CSF outflow obstruction, intracranial hypertension, lupus, MCAS, post-COVID symptoms, EDS, or other complex conditions.

When Migraine Symptoms Require Urgent Evaluation

Patients should seek urgent medical evaluation for sudden severe headache, the worst headache of their life, headache after head injury, fever, stiff neck, confusion, fainting, seizure, weakness, numbness, trouble speaking, vision loss, new neurologic symptoms, pregnancy with headache, cancer history, immune suppression, new headache later in life, or a major change in headache pattern.

These symptoms may reflect serious neurologic, vascular, infectious, inflammatory, or pressure-related conditions and should not be managed as routine migraine.

How MPM Approaches Chronic Migraine Care

MPM approaches chronic migraine through a diagnosis-first, coordinated model. The goal is to confirm the headache pattern, identify overlapping contributors, evaluate medication use, screen for red flags, and build a plan that fits the patient’s symptoms and medical history.

For patients looking for chronic migraine treatment in Manhattan, MPM offers a careful pain medicine perspective that integrates headache care, autonomic dysfunction, neck and jaw contributors, trigeminal nerve pain, hypermobility, inflammatory overlap, post-COVID symptoms, psychology of pain, and complex chronic pain.

The goal is to clarify what is driving the chronic migraine pattern and guide appropriate next steps without overpromising outcomes.