Endometriosis Pain Evaluation and Treatment in Manhattan

Endometriosis can cause pelvic pain, abdominal pain, painful periods, pain with sex, bowel or bladder pain, and persistent symptoms that may continue even after gynecology care or surgery.

Learn how Dr. Ahmed discusses endometriosis, its connection to chronic pelvic pain, and personalized treatment options to help patients find relief.

Understanding Endometriosis-Related Pain

Endometriosis is a condition in which tissue similar to the lining of the uterus grows outside the uterus. It can cause pelvic pain, painful periods, lower abdominal pain, back pain, pain with sex, pain with bowel movements, pain with urination, bloating, and fertility concerns.

For some patients, pain occurs mainly around the menstrual cycle. For others, endometriosis-related pain becomes more persistent and may occur outside the menstrual period. Pain can also continue after hormonal therapy, pelvic floor therapy, surgery, or imaging that does not fully explain the severity of symptoms.

At Manhattan Pain Medicine (MPM), evaluation focuses on the pain pathways that can overlap with endometriosis. MPM does not replace gynecology or endometriosis surgery. Instead, our role is to help identify and treat overlapping pain generators, including pelvic floor dysfunction, pudendal neuralgia, abdominal wall nerve irritation, sacroiliac joint dysfunction, hip-related pain, sympathetic pain, central sensitization, and pain-related distress.

Specialist Care for Endometriosis-Related Pelvic Pain

At MPM, endometriosis-related pain evaluation begins by mapping the pain pattern, cycle relationship, location, triggers, prior gynecology care, prior surgery, medication history, pelvic floor findings, and related bowel, bladder, hip, back, abdominal, or nerve symptoms.

For patients looking for endometriosis pain treatment in Manhattan, MPM evaluates whether symptoms may involve endometriosis lesions, pelvic floor muscle guarding, pudendal neuralgia, abdominal wall nerve entrapment, sacroiliac joint dysfunction, hip impingement, labral tears, hernia-related pain, fibroids, constipation, central pain syndromes, EDS, hypermobility, or autonomic symptoms.

Care may include medication management, pain psychology, biofeedback, acupuncture, trigger point injections, pelvic floor trigger point injections, pudendal nerve block, ganglion impar block, superior hypogastric plexus block, sacroiliac joint injection, sympathetic blocks, ultrasound-guided injections, peripheral nerve stimulation, or other selected options when clinically appropriate. MPM also coordinates with gynecology, endometriosis surgeons, pelvic floor physical therapy, GI, urology, orthopedics, and other specialists when needed.

Why Endometriosis Pain Can Persist After Treatment

Endometriosis pain can persist for several reasons. Some patients may have residual disease, recurrence, scar tissue, or ongoing inflammation. Others may develop pelvic floor guarding, nerve sensitization, abdominal wall pain, hip or sacroiliac contributors, bladder or bowel overlap, or central pain sensitization.

Persistent pain does not mean the original diagnosis was wrong. It may mean the pain has become layered over time. A patient may have endometriosis and pudendal neuralgia, endometriosis and pelvic floor dysfunction, endometriosis and hip impingement, or endometriosis and central pain sensitivity.

MPM’s diagnosis-first approach is designed to identify these overlapping pain generators and determine which treatments belong in the care plan. The goal is not to treat endometriosis lesions directly, but to help address the pain pathways that may continue to affect daily function.

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Diagnosis-first care

How MPM Approaches Endometriosis Pain Evaluation

MPM evaluates endometriosis-related pain by identifying pelvic, nerve, muscle, joint, abdominal, and central pain contributors before recommending treatment.
  • 1

    Map the Pain Pattern

    MPM begins by reviewing where the pain occurs, whether it follows the menstrual cycle, what activities or symptoms trigger it, and how it affects daily function. Pain with sex, bowel movements, urination, sitting, hip movement, pelvic pressure, or lower abdominal symptoms can provide important diagnostic clues.
  • 2

    Review Prior Gynecology Care and Surgery

    Many patients have already tried hormonal therapy, laparoscopy, excision, ablation, pelvic floor therapy, imaging, or medication. MPM reviews this history to understand what improved, what did not, and whether persistent pain may involve another pain generator beyond visible endometriosis lesions.
  • 3

    Evaluate Overlapping Pain Drivers

    Endometriosis-related pain may overlap with pelvic floor dysfunction, pudendal neuralgia, abdominal wall nerve pain, sacroiliac joint dysfunction, hip impingement, labral tears, fibroids, hernia pain, constipation, central pain syndromes, EDS, hypermobility, or autonomic symptoms. MPM evaluates these patterns in context.
  • 4

    Coordinate a Treatment Plan

    Treatment may include medication management, pain psychology, biofeedback, acupuncture, trigger point injections, pelvic floor trigger point injections, pudendal nerve block, ganglion impar block, superior hypogastric plexus block, sacroiliac joint injection, sympathetic blocks, ultrasound-guided injections, or coordination with gynecology, GI, urology, pelvic floor therapy, orthopedics, or surgery when needed.

Endometriosis Within MPM’s Pelvic Pain Framework

Endometriosis is most closely connected to MPM’s Pelvic Pain Zone of Expertise, with important overlap in Complex Chronic Pain, Autonomic dysfunction, and Psychology of Pain.
Pelvic Pain is relevant when symptoms involve the pelvis, pelvic floor, reproductive organs, bladder, bowel, pudendal nerve, sacroiliac joint, hip, abdominal wall, or tailbone. Complex Chronic Pain is relevant when symptoms persist, spread, or become layered over time. Autonomic dysfunction may be relevant when symptoms overlap with bowel changes, bladder symptoms, dizziness, nausea, fatigue, or postural symptoms. Psychology of Pain is relevant when chronic pain affects fear, sleep, stress, medical trauma, or the ability to safely reengage with care.

MPM evaluates these relationships carefully so treatment can be matched to the patient’s pain pattern rather than applied as a one-size-fits-all approach.

PATIENT STORIES

Real Patients. Real Progress.

Hear from patients who came to Manhattan Pain Medicine looking for answers, clarity, and a more thoughtful path forward.
  • Michael O.

    5 star review

    These guys are the best. I've been going here for over 6 years and their familiarity with my Schwannomatosis (most ppl have never even heard of it - its rather rare) and their ability to diagnose my CRPS quickly and accurately and then treat it like I was merely getting a flu shot is just incredible...

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  • John A.

    5 star review

    Highly recommended for those who need Pain Management. Everyone at Manhattan Pain Medicine is extremely nice and helpful. I have had very good interactions with both Dr. Siefferman and Dr. Louis. All of the staff is very responsive. 5 stars.

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  • Rakhee K.

    5 star review

    The providers at Manhattan Pain Medicine are exceptional. I wish I had found them 30 years ago!

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  • Annie R.

    5 star review

    I genuinely can’t say enough good things about the team at Manhattan Pain Medicine. I have MCAS, EDS, and an inflammatory autoimmune disease, and I’ve basically been searching for answers since I was a kid. I had years of unexplained inflammation markers, chronic pain, and allergic reactions despite...

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  • Karine S.

    5 star review

    I have a complex medical history and have seen a lot of doctors over the years. Dr. Mikaberidze and Dr. Siefferman each took the time to really listen and understand everything I had been dealing with. I also appreciated how they work together and communicated about my care. I left with a plan that...

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  • Edwin F-S.

    5 star review

    Sharing my gratitude for the pleasant experience last week during my visit, the medical team provided great care and also treated my session as a learning experience, I left my session with a wealth of knowledge. A big thank you to the kind, and professional staff who welcomed me to the office as a...

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  • Madaline. M

    5 star review

    I cannot say enough good things about Manhattan Pain Medicine. From the moment I walked in, I felt truly cared for and taken seriously. Dr. Nino Mikaberidze, Director of Rheumatology, is exceptional — knowledgeable, compassionate, and incredibly thorough. She takes the time to listen, explains every...

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  • Lauren W.

    5 star review

    Dr Siefferman is the most thorough, patient doctor I have even been to. Currently I travel from miami to nyc to see him because his bed side manner and desire to help is incomparable.

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  • Dana S.

    5 star review

    This practice is wonderful. I have been a patient of Dr. Siefferman’s since 2019 and he’s extremely helpful and kind. He has brought in a Rheumatologist who is also great. They handle very complex pain issues and always try to find new ways to help me.

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  • Frans M.

    5 star review

    Dr. Siefferman is an incredible doctor! He is extremely diligent and knowledgeable. It feels like you are his only patient. He invests a lot of time and effort into your injuries and concerns. I did not find these wonderful qualities with other pain specialists before, who were always rushed and som...

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  • Gregory S.

    5 star review

    Dr. Siefferman is a doctor who combines the old world bedside manner of doctors from my childhood (60 years ago) with a sta te of the art embrace of modern technology. It is always a pleasure to have an appointment with him...always has options and solutions to my medical issues. He is truly the doc...

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  • Judith R.

    5 star review

    Dr. Siefferman is a genius. He is very informed and listens attentively.

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  • Joshua M.

    5 star review

    Dr. Siefferman and his entire team continue to be efficient, dedicated, and driven by precision and a genuine desire to give fantastic care. Will always recommend.

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  • Michael W. S

    5 star review

    Doctor Siefferman is fantastic. Have been seeing him for 5 years. Couldn’t recommend more.

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  • Stephanie G.

    5 star review

    Dr. Siefferman is the ONLY doctor who has ever been able to diagnose my pain and treat it. He is hands down the best

    ZocDoc

Endometriosis Pain FAQs

Related conditions

Conditions That May Overlap With Endometriosis Pain

Endometriosis-related pain may overlap with pelvic pain, abdominal pain, stomach pain, ACNES, pelvic floor dysfunction, pudendal neuralgia, sacroiliac joint dysfunction, piriformis syndrome, hip impingement, labral tears, anterior pelvic tilt, fibroids, EDS, hypermobility spectrum disorder, hernia pain, femoral hernia, obturator hernia, sports hernia or athletic pubalgia, umbilical hernia, central pain syndromes, and tension headache.

Understanding Insurance Before You Begin

Before care begins, our team helps patients understand the practical side of treatment, including insurance verification, out-of-network benefits, cost-share estimates, self-pay options, and billing questions. We believe patients should have as much clarity as possible before moving forward.

Insurance & Billing

Pain Care That Starts With Understanding

When pain is complex, the first step should not be another generic treatment. Manhattan Pain Medicine looks deeper to understand what is driving the pain, why it has persisted, and what path forward makes sense for you.

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Insights & Research

Explore MPM Insights and Research, including patient-friendly articles, clinical perspectives, and research from our team to help explain how we understand complex pain, evaluate care options, and guide the path to treatment
Patient education

A Deeper Look at Endometriosis and Chronic Pelvic Pain

Endometriosis can cause pelvic pain, but persistent symptoms may also involve pelvic floor, nerve, abdominal wall, hip, SI joint, bowel, bladder, autonomic, and central pain pathways.

Endometriosis

Endometriosis is a pelvic pain condition that can affect far more than the menstrual cycle. Many patients experience painful periods, lower abdominal pain, back pain, pain with sex, pain with bowel movements, pain with urination, bloating, nausea, bowel changes, bladder symptoms, fatigue, or pain that continues outside the menstrual period.

For some patients, endometriosis is diagnosed after years of symptoms. Others are diagnosed after imaging, clinical evaluation, laparoscopy, or surgery. Some patients improve with hormonal treatment, excision, ablation, pelvic floor therapy, or other gynecology care. Others continue to have pain because the pain pattern has become more complex.

Endometriosis Pain as a Layered Condition

Endometriosis pain may begin with inflammation, lesions, adhesions, hormonal cycling, or irritation of nearby pelvic structures. Over time, pain can become layered. Pelvic floor muscles may tighten in response to pain. Nerves may become more sensitive. Scar tissue may irritate local tissues. Hip, sacroiliac, abdominal wall, bowel, bladder, and pelvic floor contributors may become part of the symptom pattern.

This is why MPM does not treat endometriosis-related pain as one single source. The goal is to identify which pain pathways are active and which specialists should be part of the plan.

Persistent Pain After Endometriosis Surgery

Some patients continue to have pelvic pain after endometriosis surgery. This can happen for many reasons. There may be residual disease, recurrence, scar tissue, pelvic floor dysfunction, abdominal wall nerve irritation, pudendal neuralgia, hip-related pain, sacroiliac joint dysfunction, bowel or bladder overlap, or central pain sensitization.

Persistent pain after surgery does not mean the pain is not real. It also does not mean the surgery was necessarily unsuccessful. It may mean the original diagnosis was only one part of a broader pain picture.

MPM evaluates persistent symptoms after endometriosis treatment by reviewing the pain pattern, surgical history, prior response to treatment, pelvic floor symptoms, bowel and bladder symptoms, hip and SI joint mechanics, nerve pain features, and central pain contributors.

Pelvic Floor Dysfunction and Endometriosis

Pelvic floor dysfunction is common in many chronic pelvic pain patterns. When the body experiences ongoing pelvic pain, the pelvic floor muscles may tighten, guard, or lose normal coordination. This can contribute to sitting pain, pain with sex, painful bowel movements, urinary symptoms, rectal pain, tailbone pain, or pelvic pressure.

Pelvic floor dysfunction can persist even after endometriosis lesions are treated. For some patients, pelvic floor physical therapy is an important part of care. For others, pain medicine evaluation may help identify whether pelvic floor trigger points, nerve irritation, or sympathetic pain pathways are also contributing.

Endometriosis and Nerve Pain

Endometriosis-related pain can overlap with nerve sensitization. Some patients describe burning, electric, shooting, sharp, tingling, or numb pelvic pain. Others have pain that worsens with sitting, bowel movements, urination, intercourse, movement, or specific positions.

Nerve-related pelvic pain may involve pudendal neuralgia, abdominal wall nerve irritation, scar-related nerve pain, sacral nerve irritation, pelvic nerve sensitization, or sympathetically mediated pain. MPM evaluates the location, sensation, triggers, prior procedures, pelvic floor findings, and neurologic symptoms to determine whether nerve-targeted care may be appropriate.

Bowel, Bladder, and Abdominal Pain Overlap

Endometriosis can be associated with bowel or bladder pain, especially when symptoms flare around the menstrual cycle. Pain with bowel movements, constipation, diarrhea, bloating, urinary pain, bladder pressure, and lower abdominal pain may all overlap with pelvic pain.

These symptoms require careful evaluation because they may also reflect GI, urologic, pelvic floor, abdominal wall, or nerve-related conditions. MPM does not replace gastroenterology or urology when those evaluations are needed. Instead, MPM helps assess whether pain pathways are contributing to ongoing symptoms after serious or organ-specific causes have been considered.

Hip, Sacroiliac, and Musculoskeletal Contributors

Pelvic pain may also overlap with hip and musculoskeletal conditions. Hip impingement, labral tears, sacroiliac joint dysfunction, anterior pelvic tilt, piriformis syndrome, abdominal wall pain, hernia-related pain, and pelvic instability can all create symptoms that may feel pelvic or gynecologic.

This overlap is especially important for patients with EDS or hypermobility spectrum disorder. Joint laxity, altered mechanics, muscle guarding, and connective tissue differences may contribute to hip pain, SI joint pain, pelvic floor overactivity, and abdominal wall or nerve sensitivity.

MPM evaluates these musculoskeletal contributors as part of the broader endometriosis-related pain picture.

Central Sensitization and Endometriosis Pain

When pelvic pain persists over time, the nervous system can become more sensitive. This process is often called central sensitization. It can make pain feel stronger, spread beyond the original location, or continue even after the visible tissue findings have changed.

Central sensitization does not mean pain is imagined. It means the nervous system has become part of the pain experience. Endometriosis-associated pain may also overlap with fibromyalgia-like symptoms, headaches, abdominal pain, pelvic floor dysfunction, sleep disruption, anxiety around symptoms, and medical trauma.

Pain psychology, biofeedback, pacing, sleep support, and nervous system regulation can be part of care for selected patients. These tools are not replacements for gynecology care. They help address the ways chronic pain affects the body, brain, behavior, and daily function.

Treatment Options for Endometriosis-Related Pelvic Pain

Treatment depends on what is driving the pain. Some patients need ongoing gynecology care, hormonal management, endometriosis surgery evaluation, pelvic floor physical therapy, GI care, urology care, or fertility-related support.

From a pain medicine perspective, selected options may include medication management, pain psychology, biofeedback, acupuncture, trigger point injections, pelvic floor trigger point injections, pudendal nerve block, ganglion impar block, superior hypogastric plexus block, sacroiliac joint injection, sacrococcygeal ligament injection, sympathetic blocks, lumbar sympathetic blocks, ultrasound-guided injections, ketamine therapy, lidocaine and ketamine infusions, or peripheral nerve stimulation.

These treatments are not routine for every patient with endometriosis. They are considered only when the diagnosis, anatomy, pain pattern, severity, risk profile, and goals support them.

When Gynecology or Surgical Care Is Needed

Endometriosis requires appropriate gynecologic evaluation. Patients may need imaging, hormonal management, medical therapy, laparoscopy, excision consultation, fertility evaluation, or surgical care depending on symptoms and goals.

MPM does not treat endometriosis lesions directly and does not replace endometriosis surgery when surgery is indicated. MPM’s role is to help evaluate and manage the pain pathways that may overlap with endometriosis, especially when symptoms persist, become chronic, or involve nerve, muscle, joint, abdominal wall, or central pain contributors.

When Symptoms Require Urgent Evaluation

Patients should seek urgent evaluation for sudden severe pelvic or abdominal pain, fainting, fever, vomiting, heavy bleeding, pregnancy with pelvic pain, suspected ectopic pregnancy, blood in stool or urine, inability to urinate or pass stool, rapidly worsening symptoms, new neurologic deficits, signs of infection, or severe pain that feels different from prior episodes.

Pain procedures should not replace appropriate gynecologic, emergency, urologic, GI, surgical, neurologic, or oncologic evaluation when those are needed.

How MPM Approaches Endometriosis Pain Care

MPM approaches endometriosis-related pain through a diagnosis-first, coordinated model. The goal is to understand whether pain is related to pelvic floor dysfunction, nerve irritation, abdominal wall pain, hip or SI joint mechanics, bowel or bladder overlap, scar tissue, sympathetic pain, central sensitization, or other contributors.

For patients looking for endometriosis pain treatment in Manhattan, MPM offers a careful pain medicine perspective focused on source-finding, patient education, symptom validation, and coordinated treatment planning. Care is individualized and may involve conservative strategies, pelvic floor coordination, pain psychology, biofeedback, medication management, selected image-guided procedures, nerve blocks, or referral to the appropriate specialist when needed.